Bulletin Board of Oral Pathology
Bulletin Board of Oral Pathology
Forum for Clinical and Surgical Oral Pathology
Case BBOPF 12-1
MESSAGE FROM THE MANAGER
The following is the summary of the 21 responses elicited by Dr.
Baratz's case. In addition, Dr. Baratz is giving us "..the rest of the story."
In case you may wish to view this case again, the URL is:
http://dental.buffalo.edu/bbop/forum/case201201.asp
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DIAGNOSIS
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| Herpes zoster (acyclovir, famcyclovir, valacyclovir) | 6 |
| Herpes simplex (famcyclovir, valacyclovir) | 5 |
| Eczema herpeticum (acylovir, famcyclovir) | 3 |
| Molluscum contagiosum (Imiquimod) | 2 |
| Allergic contact dermatitis | 1 |
| Kaposi’s varicelliform eruption | 1 |
| Atypical bilateral VZV infection (antiviral agent) | 1 |
| Zoster following cephalexin use | 1 |
| Cutaneous cryptococcosis (amphotericin- B) | 1 |
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THE REST OF THE STORY
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Dear Colleagues:
My recent case posted on BBOP (12-01) had a diagnosis of Eczema Herpeticum. Herpes simplex infection which super-infected his atopic eczema outbreak.
The treatment was intravenous acyclovir, followed by oral acyclovir, plus high potency topical steroids. The patient responded quickly.
A great classic early review is available for free on the Web at PubMed.
PMID:
4004311
[PubMed - indexed for MEDLINE]
PMCID: PMC1777248
Free PMC Article
T J DAVID AND M LONGSON
Archives of Disease in Childhood, 1985, 60, 338-343 Herpes simplex infection in atopic eczema
Putting the search term: “eczema herpeticum” into Pub Med will
lead you to some interesting, and more recent, papers on this fascinating problem, with many commenting on why and how it occurs, including the paper referenced below.
Readers interested in the immune response and a more recent review of this fascinating condition will likely find this second paper, noted below, of interest. It is also available for free on PubMed, by
following this link: Free PMC Article
Br J Dermatol. 2010 Sep;163(3):659-61. doi: 10.1111/j.
1365-2133.2010.09892.x. Epub 2010 Jun 9.
History of eczema herpeticum is associated with the inability to induce human ß-defensin (HBD)-2, HBD-3 and cathelicidin in the skin of patients with atopic dermatitis.
Hata TR, Kotol P, Boguniewicz M, Taylor P, Paik A, Jackson M, Nguyen M, Kabigting F, Miller J, Gerber M, Zaccaro D,Armstrong B, Dorschner R, Leung DY, Gallo RL.
PMID:
20545685
[PubMed - indexed for MEDLINE]
PMCID: PMC2966528
Free PMC Article
Best regards,
Bob Baratz
If you wish to post a case in the BBOP Forum for Clinical and Surgical Pathology, please contact Dr. Alfredo Aguirre.
2/9/2012