Bulletin Board of Oral Pathology
Forum for Clinical and Surgical Oral Pathology Case BBOPF 03-3 The following case was contributed by Dr. Jonathan Tversky (Specialist in Oral Medicine, Melbourne, Australia) and was posted from March 26 to April 10, 2003. Dr. Tversky is requesting your comments for the ensuing case. Please send your diagnosis/suggestions in the window below the accompanying images. A summary of the responses will be posted in BBOP. Clinical HistoryA 21 year old female presented with a 7 month history of enlarging scales on her lips. In the last 2 months, she developed patchy grey areas on the skin of her face and hands. InvestigationsHistopathology: Profound hyperorthokeratosis, slightly irregular acanthosis with patchy spongiosis and minimal perivascular lymphocytic inflammation in the superficial stroma. Conclusion: Limited spongiotic dermatitis consistent with an eczematous process. Clinical & Laboratory Investigations by a dermatologist, a physician, a gastroenterologist and an oncologist have ruled out Acrodermatitis Enteropathica and Acanthosis Nigricans. Patch Testing was non-contributory. Images
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Case prepared by Dr. Alfredo Aguirre (BBOP Manager) and Daniel Emmer (Web Administrator, University at Buffalo School of Dental Medicine).