Forum for Clinical and Surgical Oral Pathology

Case BBOPF 03-1

The following case was contributed by Dr. Ross Kerr (NYU College of Dentistry) and was posted from February 20 to March 3, 2003. Dr. Kerr is requesting your opinion about treatment options for one of his patients. Please send your comments either directly to Dr. Kerr at ark3@nyu.edu or write your comments in the window below the 4 accompanying images.

Clinical History

48 year old male with stable HIV disease (he's been HIV + for over 15 years and a long-standing (>4 years) severe hpv infection. The patient has been to multiple providers and received a range of therapies including carbon dioxide laser ablation, topical podophyllum resin, and interferon injections (both intralesional and systemic). He rebounded with more widespread disease following laser therapy alone. I don't have a clear history of the podophyllum resin application regimen but he thought it helped somewhat. The interferon worked best (don't have the exact dosage history) but he suffered a severe leukopenia/anemia following systemic injections. He is presently applying imiquimod to his lips with mild benefit.

Images

Case prepared by Dr. Alfredo Aguirre (BBOP Manager) and Daniel Emmer (Web Administrator, University at Buffalo School of Dental Medicine).