Bulletin Board of Oral Pathology

Forum for Clinical and Surgical Oral Pathology

The following case originated from upstate New York. The case was be posted from July 27 to August 16, 1998.  A summary of the responses is available here.
 

Clinical History

A 10 month-old girl presented with an expansile 1.5 cm firm mass of the left anterior maxilla. Radiographically, the tumor was lucent, primarily unilocular and exhibited expansile borders although a small erosion through the palate was indicated. Developing tooth buds noted on the contralateral side seemed to be caught up in this process.

The following are 8 representative microscopic fields (stained with H&e) of the tumoral mass. Clicking any small image will present a much larger version of the image in a separate browser window. After viewing an image in this separate window, you may close, hide, or minimize that window and return to this page.

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Fig. 1a. Low power view showing a cystic space lined by odontogenic epithelium (upper field). Surrounded by surgical hemorrhage is a rim of ameloblastic epithelium capping ectomesenchymal tissue. The lower field shows the emergence of ameloblastic epithelium from the cystic lining. (0.5 x) Figures 1b and 1c are higher magnifications (2 x)

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Fig. 2. Low power view demonstrates a solid lesion. (0.5 x)

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Fig. 3. Low power view reveals odontogenic epithelium with plexiform and follicular patterns.  The connective tissue stroma is highly cellular. (2.3 x)
 

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Fig. 4. This magnification discloses the presence of ameloblastic epithelium in a highly cellular stroma. (6.3 x)

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Fig. 5. This field shows a highly cellular and myxomatous stroma. Mitotic activity is observed. (40 x)

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Fig. 6. At least three mitotic figures are observed in this slide.  The upper right field shows a row of basal cells of the ameloblastic epithelium.  (40 x)

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Fig. 7. Island of ameloblastic epithelium showing mitotic activity. (40 x)

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Fig. 8. Ameloblastic epithelium with a follicular configuration and a mitotic figure in the "stellate-reticulum"-like area. (40 x)

 

Case prepared by Dr. Alfredo Aguirre, Dr. Alan Drinnan (BBOP Managers) and Daniel Emmer (Web Administrator, University at Buffalo School of Dental Medicine).

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